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1.
researchsquare; 2022.
Preprint in English | PREPRINT-RESEARCHSQUARE | ID: ppzbmed-10.21203.rs.3.rs-2382470.v1

ABSTRACT

We tracked the effective reproduction number Rt of Omicron BF.7 in Beijing in November – December 2022 by fitting a transmission dynamic model parameterized with real-time mobility data to (i) the daily number of new symptomatic cases on November 1–11 (when the zero-covid interventions were still strictly enforced) and (ii) the proportion of individuals who participated in online polls on December 10–14 and self-reported to have been previously test-positive. After the announcement of “20 measures”, we estimated that Rt increased to 3.42 (95% CrI: 2.79–4.17) on November 18. Infection incidence peaked on December 10, and the cumulative infection attack rate was 42.5% (95% CrI: 20.3–63.9) on December 14. Surveillance programmes should be rapidly set up to monitor the evolving epidemiology and evolution of SARS-CoV-2 across China.

2.
researchsquare; 2021.
Preprint in English | PREPRINT-RESEARCHSQUARE | ID: ppzbmed-10.21203.rs.3.rs-880508.v1

ABSTRACT

We examined the potential additional risk of adverse events of special interest (AESI) within 28 days post-Covid-19 vaccination with CoronaVac or Comirnaty (Pfizer-BioNTech) imposed by multimorbidity (2 + chronic conditions). Using a territory-wide public healthcare database with linkage to population-based vaccination records in Hong Kong, we conducted a retrospective cohort study of patients with chronic diseases. Thirty AESI according to World Health Organization’s Global Advisory Committee on Vaccine Safety were examined. In total, 883,416 patients were included. During follow-up, 2,807 (0.3%) patients had AESI. Weighted Cox models suggested that vaccinated patients had lower risks of any AESI than those unvaccinated, that multimorbidity was associated with an increased risk regardless of vaccination status, and there was no significant effect modification of the association of vaccination with AESI by multimorbidity status. To conclude, we found no evidence that multimorbidity imposes extra risks of AESI within 28 days following Covid-19 vaccination.


Subject(s)
COVID-19 , Chronic Disease
3.
preprints.org; 2021.
Preprint in English | PREPRINT-PREPRINTS.ORG | ID: ppzbmed-202009.0658.v2

ABSTRACT

Objective: We tested a model of individual health literacy information sharing with family members, personal preventive behaviours and family well-being during the Coronavirus Disease 2019 (COVID-19) pandemic in Hong Kong. Methods: We analysed data of 1501 randomly selected Chinese adults from a cross-sectional survey in Hong Kong from 9 to 23 April, 2020. Individual health literacy about COVID-19 with the items extracted from the questionnaire in World Health Organization Risk Communication and Community Engagement (RCCE) Action Plan Guidance for COVID-19 preparedness and response, COVID-19 information sharing with family members, preventive behaviours against COVID-19 and family well-being were measured. Structural equation modelling analysis tested the proposed model. Findings: COVID-19 information sharing with family members partially mediated the association between individual health literacy and personal preventive behaviours. The direct effect of 0.24 was shown, and the indirect effect through COVID-19 information sharing with family members was small at 0.03 (Z = 3.66, p < 0.001). Family well-being was associated with personal preventive behaviours against COVID-19. The model was adjusted for sex, age, and socioeconomic status factors and had good fit with RMSEA = 0.04, CFI = 0.98, TLI = 0.96, and SRMR = 0.02. Conclusion: COVID-19 information sharing with family members was a partial mediator between individual health literacy and personal preventive behaviours against COVID-19. Strategies for enhancing health literacy and preventive measures against COVID-19 are needed to promote family well-being in the pandemic.


Subject(s)
COVID-19
4.
preprints.org; 2020.
Preprint in English | PREPRINT-PREPRINTS.ORG | ID: ppzbmed-10.20944.preprints202009.0658.v1

ABSTRACT

Objective: We tested a model of individual health literacy, information sharing with family members, personal preventive behaviours and family well-being during COVID-19 pandemic in Hong Kong. Methods: We analysed data of 1501 randomly selected Chinese adults from a cross-sectional survey in Hong Kong from 9 to 23 April 2020. Individual health literacy, COVID-19 information sharing with family members, preventive behaviours against COVID-19 and family well-being were measured. Structural equation modelling analysis tested the proposed model. Findings: COVID-19 information sharing with family members partially mediated the association between individual health literacy and personal preventive behaviours. The direct effect of .24 was shown and indirect effect through COVID-19 information sharing with family members was small with .03 (Z = 3.66, p < .001). Family well-being was associated with personal preventive behaviours against COVID-19. The model was adjusted for sex, age, and socioeconomic status factors and had good fit with RMSEA = .04, CFI = .98, TLI = .96, and SRMR = .02. Conclusion: COVID-19 information sharing with family members was a partial mediator between individual health literacy and personal preventive behaviours against COVID-19. Strategies for enhancing health literacy and preventive measures against COVID-19 are needed to promote family well-being in the pandemic.


Subject(s)
COVID-19
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